Rapid Aneuploidy and CNV Detection in Single Cells using the MiSeq System Comparison between data generated from single cells using 24sure® array-based screening and next-generation sequencing (NGS) using the MiSeq System. Figure 1: Common Workflow between Arrays and Sequencing

IVF success rates are low, with approximately one-third of all cycles resulting in live births1. Improving IVF success rates would make a significant difference in the lives of many women trying to conceive. Chromosome aneuploidy (abnormal number of chromosomes) is a major cause of IVF failure, miscarriage, and, in rare cases, abnormal pregnancy and live birth. Most aneuploidies arise during the final stages of egg development and increase exponentially with maternal age. Selectively implanting euploid (normal number of chromosomes) embryos is critical to reducing miscarriage and improving IVF success. Early clinical experience show improvements as high as 50% in IVF success rates using embryos selected by the 24sure test2.